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The December 2025 Phase 3 TRIUMPH-4 results were even more impressive, with the 12mg group losing an average of 28.7% of body weight over 68 weeks
It emphasizes the need for exact dosing protocols to balance efficacy with organ stress
Aqueous solvents such as sterile water or bacteriostatic water are preferred for in vivo rodent studies because they eliminate the confounding variable of DMSO's own biological activity, which includes membrane permeabilization and anti-inflammatory effects
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