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it was early recognised that APAP was hepatotoxic at high doses3 but that there were marked species differences in sensitivity.4 Further, these early studies established that a metabolite of APAP, rather than the drug itself, was the cause of its hepatotoxicity

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In line with their finding that diet is an important driver of gut microbiota composition, Yatsunenko et al

10.1016/j.jnutbio.2012.05.003 63 YantL