If this dilation of lymphatic vessels is consistent with lymphostatic decompensation (failure of lymphatic vessel function) in lipedema as the authors suggest, then salt should be found in the skin of women with lipedema as lymphatic vessels regulate Na+, Cl and water in the skin, where reduced lymphatic vessel numbers are paralleled by increased blood pressure (82)
Slower systemic results: For musculoskeletal injuries or systemic inflammation, oral dosing may be less effective
It is also, notably, the same property that makes systemic dosing worth scrutinizing: a molecule whose defining feature is carrying copper is a molecule whose systemic use has to be evaluated in light of how the body already manages copper
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International Journal of Molecular Sciences 25(14)
Your provider can run a full panel (including cortisol and fasting insulin) to see whether stress, sleep, or thyroid issues are also contributing
