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3.5 Sensitivity analysis The reason for statistical heterogeneity might be inconsistent dose and duration of administration between studies

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The insulinotropic effects of GLP-1, and the reduction of its effects in type 2 diabetes mellitus (T2DM), have made GLP-1 an attractive option for the treatment of T2DM

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Scenario 4: Switching vial concentrations mid-treatment Your pharmacy sends a 5mg/mL vial one month and a 2.5mg/mL vial the next

Semaglutide works for weight loss by mimicking the action of incretin, a natural gut hormone, particularly GLP-1, and targeting GLP-1 receptors in the brain that control appetite and slow down how quickly the stomach empties, making you feel fuller for longer