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The rates are broadly comparable when adjusted for dose equivalence
NICE estimated that 3.4 million people in England are eligible under the full criteria, but only around 220,000 will access it on the NHS in the first three years
Mangosteen, for example, slows blood clotting and can interfere with donepezil (a drug for Alzheimers).11 Additionally, its important to mention that the vitamin and mineral doses in Grns Cubs may be too high for kids 2-3 years old particularly the fat-soluble vitamins A, D, E, and K.15 The most worrisome one is vitamin A, which is offered in a 149% Daily Value (DV) dose for kids aged 2-3 (this drops to a safer 50% DV dose for kids over age four)
Another recently published review (Wu et al., BMC Medicine, 2025 ) looked at a range of studies on this subject to provide an overview of what happens when these medications are stopped
There can be nutritional issues and true adverse side effects. Common side effects include nausea (44% of patients), diarrhea, vomiting and constipation
Role of insulin resistance in the development of nonalcoholic fatty liver disease in people with type 2 diabetes: From bench to patient care
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