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For type 2 diabetes management, other medication classes (SGLT2 inhibitors, metformin) offer different mechanisms of action

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While this effect has not been conclusively demonstrated in humans, the FDA requires that semaglutides labeling includes a warning about potential thyroid risks

The melanocytes themselves may be enlarged depending on the age of the patient , further enhancing the histologic similarity

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New England Journal of Medicine, 381 (9), 841-851