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Diagnostics 13 , 1166 (2023)
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doi: 10.1186/14712466-1486 245 MerraG

Serious Side Effects and Sequelae Acute Pancreatitis: Severe abdominal pain and persistent vomiting, requiring emergency treatment.Gallbladder Disease: Gallstone formation, right upper quadrant pain, and indigestion.Cardiocardiac Problems: Irregular heartbeat, palpitations, or abnormal blood pressure.Severe Allergic Reactions: Difficulty breathing, Facial swelling, generalized rash Mood changes: Depression, anxiety, suicidal tendencies (reported rate 1-5%) Long-term risks: Thyroid C-cell tumor: Warning in animal studies, indicated by a black border on the packaging Deteriorating kidney function: Increased renal burden for long-term users Recurrence of pancreatitis: Increased risk of recurrent attacks Weight rebound: Rapid return to original weight within months of discontinuation Nutritional imbalance: Appetite suppression leading to vitamin and mineral deficiencies Pre- and post-use management Before use: Check liver and kidney function and baseline blood glucose

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