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In SURMOUNT-1 the 15 mg arm averaged 22.5% body weight loss at 72 weeks, only modestly higher than the 10 mg arm at 21.4%

Synergistic action of active substances

Gradientdose 5-amino-1-methylquinolinium treatment further enables investigation of doseresponse relationships between NNMT inhibition, NAD+ levels, and metabolic efficiency, improving mechanistic understanding and supporting targetbased research for metabolic diseases

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