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All recommendations by the ADA regarding GLP-1 RAs have been assigned an A rating, which is the associations highest rating of evidence

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Wang J, Zhou Y, Long D, Wu Y, Liu F

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doi: 10.1016/j.conb.2017.05.018 49

Relatively, exenatide ER was therefore 37% as efficacious as once-weekly semaglutide 1.0 mg, while dulaglutide 0.75 mg and 1.5 mg were respectively 47% and 68% as efficacious as once-weekly semaglutide 0.5 mg and 33% and 47% as efficacious as once-weekly semaglutide 1 mg for reducing HbA1c by 1.0% while lowering weight by 5.0% (Figs