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The injected hydroxocobalamin is transported via the bloodstream to tissues throughout the body, where it acts as a cofactor for two critical enzymatic reactions: the conversion of homocysteine to methionine and the conversion of methylmalonyl-CoA to succinyl-CoA

Glutathione measurements Total glutathione levels and redox potential were determined using HPLC to determine glutathione metabolites following derivatization with dansyl chloride

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Newer studies show it can also help inhibit molecular markers of oxidative stress like MMP-1 and MMP-9, enzymes that break down collagen

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A 10-parameter panel, including not only classical antioxidant tests (FRAC, Trolox, DPPH) but also endogenous antioxidant enzymes and protein degradation, has shown its advantages in stratifying OS status in different HTN degrees (Nuez-Sells et al., 2019)