Many preclinical studies have demonstrated that the expression of key enzymes for GSH synthesis (GCL, SLC7A11, GS) and GSSG reduction-related enzymes (G6PD, NADPH, and GR) is downregulated in myocardium exposed to pathological factors [40, 43,44,45,46,47,48,49,50]
The "copper uglies" is the colloquial name for the temporary inflammatory or breakout-like reaction many users experience when they start using copper peptides
doi:10.1172/JCI73939 232
The caveat is that the study was done in mice, not humans, so we cant say for sure that thats going to apply to humans
The deep sapphire blue is a natural characteristic of the high-purity copper
Dermatol Ther