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In a phase II trial, adults with a BMI of 30 or 27 kg/m with comorbidities were randomized to receive efpeglenatide at doses of 4 mg weekly, 6 mg weekly, 6 mg biweekly, or 8 mg biweekly, or a placebo, all combined with a hypocaloric diet [17]

provides polyphenols when taken orally, no significant weight loss impact [14] Cinnamon extract: included for blood sugar support

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Because tirzepatide activates two receptor pathways compared to semaglutides one, the GI burden can be greater for certain individuals

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