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As emphasized, this was based on the compelling evidence collected from various models, a multitude of targets, and BPC 157s overwhelming action versus the simultaneous application of NO-agents, whether given alone, including L-NAME (NOS-blockade) and L-arginine (NOS-substrate, NO-over-stimulation), or together, including L-NAME+L-arginine, NO-inhibition, NO-overactivity, and NO-immobilization