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Serious genitourinary infections, including urosepsis, pyelonephritis, and necrotizing fasciitis of the perineum (Fournier's gangrene, a rare life-threatening infection requiring urgent surgical intervention), have occurred in patients with and without diabetes mellitus receiving SGLT2 inhibitors, including JARDIANCE [see Adverse Reactions (6.2)]

10.1080/1745039X.2023.2199806 37

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HPLC quantification accuracy decreases as purity approaches 100% due to baseline noise, integration limit uncertainty, and co-eluting trace impurities below detection limits

For example, amylin receptor (AMYR) agonists are an emerging class of anti-obesity medications

[DOI] [PubMed] [Google Scholar] 44.Baiano A., del Nobile M.A