This may be due to reduced neutrophil infiltration, matrix metalloproteinase 9 (MMP9) levels, and cysteine availability, which impaired the synthesis of collagen, secreted protein acidic and rich in cysteine (SPARC), and cysteinyl leukotrienes, all of which contribute to fibrotic remodeling [126]
Unintended consequences of obesity pharmacotherapy: a nutritional approach to ensuring better patient outcomes
Dizziness upon standing and difficulty concentrating or remembering tasks reflect reduced oxygen delivery to the brain and muscles
They slow gastric emptying, prolong satiety, and may dampen neural reactivity to food cues that trigger binge episodes
Development 143 , 554565 (2016)
Hence, GST overexpression is known to be one of the underlying reasons for therapeutic resistance in some cancers (Gamcsik et al., 2012)