Amjad, S
PMID 8948633
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Depending on the dose, a fraction of APAP is converted into a highly reactive toxic intermediate, N-acetyl-p-benzoquinone imine (NAPQI), by several P450 cytochromes [34]
This octadecapeptide (18 amino acid units) has the composition: Arg,Asp 2 ,Glu 2 ,Gly 2 ,His,Lys 2 ,Met,Phe,Pro 3 ,Ser,Tyr 2 , and is abbreviated P 18