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doi: 10.1038/s41591-023-02543-w

Every program begins with a comprehensive biomarker assessment, followed by a personalized healthspan strategy that evolves quarterly as results unfold

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Specifically, eligible studies included participants (P) with a confirmed diagnosis of vitamin B12 deficiency, interventions (I) involving oral or sublingual vitamin B12 administration, comparators (C) using intramuscular supplementation, and outcomes (O) reporting changes in serum vitamin B12 or homocysteine levels

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