In addition, significant benefit was proved with ataluren compared to placebo in key secondary endpoints, including the NorthStar Ambulatory Assessment (p=0.0283), 10-meter walk/run (p=0.0422), 4-stair climb (p=0.0293), and time to 10% worsening of 6MWD (p=0.0078)
Source list Boye, K., Ross, M., Mody, R., et al
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The choice depends on the research model, the desired duration of action, and whether the study is focused on sustained exposure or pulsatile signaling
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