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It has been reported in the literature that 1,25(OH)2D3 alleviated high-glucose-induced oxidative stress in human umbilical vein endothelial cells (HUVEC) via the upregulation of the nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant signalling pathway in a VDR-dependent manner

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Plant Cell Physiol 34:421429 Navabpour S, Morris K, Allen R, Harrison E, Mackerness AH, Buchanan-Wollaston V (2003) Expression of senescence-enhanced genes in response to oxidative stress

And I mean, like I said, it's good timing

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This supports good solubility and stability in aqueous buffers for use in in vitro, ex vivo, and in vivo research models