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10.1186/s11689-019-9277-x 80

In the late 1950s, dopamine was recognized as a neurotransmitter in its own right

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Across in vitro and preclinical models, GHK-Cu has been studied for its influence on gene expression programs related to matrix synthesis and remodeling, antioxidant defenses, and pathways associated with cellular senescence markers

Vitamin B1 and B6 are particularly active in the methionine cycle and citric acid cycle, integral processes in mitochondrial energy production