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The proposed mechanism involves MMP-1, a specific matrix metalloproteinase

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Small, unmodified peptides such as Sermorelin, Tesamorelin, and DSIP are cleaved by serum proteases within minutes, while lipidated or albumin-binding analogs such as Semaglutide, Tirzepatide, and Retatrutide remain detectable for days

Research suggests it encourages the breakdown of stored fat without significantly affecting blood sugar or acting through the IGF-1 pathway

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