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7 days) alleviates DSS-induced colitis in male C57BL/6J mice, as shown by reduced clinical activity, improved intestinal barrier integrity, and modulated gut microbiota [6]

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34 Furthermore, ALA has been found to act as an inhibitor of nuclear factor-B (NFB), suggesting a mechanism for its anti-inflammatory properties

The tolerability advantage of dual agonists over single agonists surprised many researchers

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