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Early-stage patients have fewer helpful commensals, but advanced PD is characterized by a greater dominance of exploitative or pathogenic taxa, indicating a growing inflammatory and metabolic imbalance [43]

The peptide triggers gene expression changes in over 4,000 genes that persist beyond the moment of injection (Pickart & Margolina, 2018)

These superantigens do not have to be stimulated by Langerhans cells, and they can activate many lymphocytes via non-specific receptors ( Briganti et al