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There is a significant association between PD and type 2 diabetes mellitus (T2DM), possibly due to shared pathological mechanisms such as insulin resistance, chronic inflammation, and mitochondrial dysfunction

While mild nausea, reduced appetite, and occasional stomach discomfort are expected during the first weeks of semaglutide therapy, worsening or prolonged symptoms warrant professional evaluation

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doi:10.1007/s11357-014-9615-6 Sekhar RV, Patel SG, Guthikonda AP, Reid M, Balasubramanyam A, Taffet GE, Jahoor F (2011) Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation

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