The patient had previously been treated with tirzepatide but reportedly achieved only moderate weight loss, and Muniyappa advised against bariatric surgery given the patient's age and comorbidities
Studies have shown that even multiple rises of retatrutide are well-tolerated by people with T2D, and it improves overall cardiometabolic risk measures, irrespective of dosage
Clinicians should continue to monitor trade-offs being GLP-1s and surgical treatment, researchers said
The curve climbs faster because you are adding a larger dose on top of an already-established baseline
Tirzepatide: SURPASS-2 study In the SURPASS-2 study, tirzepatide (Mounjaro) lowered A1C and led to more weight loss than semaglutide (Ozempic) in adults with type 2 diabetes
There is no MHRA-approved indication for GLP-1 receptor agonists in Hashimoto's thyroiditis, and any such use would be off-label