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Ozempic was (and still is) not FDA-approved for weight loss in patients without diabetes

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Merritt et al, included 1686 schizophrenia patients and 1451 HV, reported increased Glu and Glx in the basal ganglia (including the caudate, putamen and pallidum), elevated Glx in the medial temporal lobe and increased Gln in the thalamus [40]

Those with normal-transit constipation may even have daily bowel movements, yet describe themselves as constipated due to a persistent sense of difficult evacuation, with hard stools and abdominal bloating and discomfort

doi: 10.5114/aoms.2019.86061 70

Lixisenatide The FDA approved lixisenatide, marketed as Adlyxin, in 2016 for Type 2 diabetes