Understanding their mechanism of action provides a framework for optimizing efficacy, minimizing side effects, and expanding applications beyond diabetes to include other areas such as the treatment of obesity, cardiovascular diseases, non-alcoholic fatty liver disease (NAFLD), and even neurodegeneration
To ensure safety and efficacy, its essential to work closely with your healthcare provider, who can monitor your progress and adjust your treatment plan as needed
Alex Azar, former Secretary of the US Department of Health and Human Services, noted that there is little stigma around taking a statin to manage high cholesterol, but using a GLP-1 to help with weight loss can be perceived by some as taking the easy way out. Panelists emphasized that this perception, despite its inaccuracy, persists and may stand in the way of patients accessing these effective treatments or staying on them long-term
Their combined use could lead to faster and more effective fat loss
Furthermore, it can improve the potential of mitochondria in ATP production and increase motility with transfer of long-chain fatty acid across mitochondrial inner membrane
doi:10.1056/NEJMoa2502082 Verma S, Bttcher M, Brown P, et al
