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Regarding safety, FMT currently lacks standardized donor screening criteria, and safe abundance thresholds for potentially harmful bacteria such as Streptococcus remain undefined, raising concerns that inappropriate transplantation may exacerbate autoimmunity

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K ATP channels, which are sensitive to intracellular ATP levels, also contribute to vascular smooth muscle relaxation and play a role in cardioprotection during ischemic events (Vishwakarma et al., 2019)

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