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An engaged user is defined as a participant who completed the 24-week intervention and took any in-app action during the maintenance phase (weeks 24-65)

Absolute contraindications to GLP-1 receptor agonists include: Personal history of medullary thyroid carcinoma Family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Pregnancy (for weight management indications) Severe gastrointestinal disease, including gastroparesis Patients should be specifically questioned about these conditions during pre-treatment evaluation

Researchers should understand both the available data and its limitations