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The others have compelling anecdotal data and decent mechanistic logic, but far fewer robust human trials for fat loss specifically

Figure 5 : Overlap of obesity and diabetes With Lilly and Novo Nordisk currently the only two companies with approved weight loss medications in the US and international markets, the companies generated a combined $32bn in the US market last year alone and almost another $10bn outside the US

Linge, J., Birkenfeld, A

Tirzepatide is a dual agonist (GIP + GLP-1)

Confirm when your first renewal date is, how to cancel (requires active contact with care team), and what happens to a multi-month discounted plan if you want to exit early