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Diet is the primary defense against rebound weight gain because it directly controls energy balance independent of medication

After pressing the injection button, patients should follow the specific hold time in their device instructions (which may vary by product) before withdrawing the needle to ensure complete dose delivery and prevent medication leakage

Following the SCALE clinical trial program, it received a second FDA approval in December 2014 as Saxenda for chronic weight management making it the first GLP-1 agonist approved for obesity treatment

The efficacy of GLP-1 analogues on appetite parameters, gastric emptying, food preference and taste among adults with obesity: Systematic review of randomized controlled trials

It helps reduce body weight by promoting feelings of satiety and fullness, leading to decreased calorie intake

Three general approaches exist for long term management