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Cheng KK, Lam KS, Wang Y, Huang Y, Carling D, Wu D, Wong C, Xu A

The benefits in ASCVD risk reduction with GLP-1RA are evidenced by 14% risk reduction in cardiovascular mortality with an NNTB of 207 to prevent one event, 13% MACE reduction with an NNT of 67 to prevent one event and 12% risk reduction in stroke with an NNT of 335 to prevent one event, along with their favourable safety profile of 6% increased overall adverse events

The panel noted that the term originated from patient anecdotes, particularly from people who noticed that food noise suddenly disappeared after starting GLP-1 treatment, and that the scientific community has since moved to study it more rigorously

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