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However, caution should be taken when interpreting these results due to short follow-up periods (i.e., 1.11.4 years [18,19,20]), the possibility of confounding bias caused by the inclusion of advanced T2D cases (i.e., requiring intensive insulin therapy [18]), uncertain liver effects (e.g., incident NAFLD) of active comparators (i.e., DPP4is [19, 20] and insulin [18]), lack of dose-response analysis, and limited generalizability to other ethnic populations

In Great Britain, tirzepatide is also available under the brand name Zepbound for chronic weight management in adults with obesity or overweight with weight-related comorbidities

LL-37 is a synthetic cathelicidin-derived peptide (37 amino acids)

However, pharmacokinetic clearance and symptomatic resolution are not identical

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We always recommend using bacteriostatic water