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Melatonins decline in aging has widespread implications weakening circadian coordination, diminishing sleep quality, lowering antioxidant defense, increasing inflammation, and reducing neuroprotection, all of which may contribute to accelerated aging and age-related diseases

The safer conversation is about eligibility, monitoring, and whether the proposed combination has a legitimate clinical basis

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Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

Cell, 2005)

Prim Care Companion CNS Disord 2025;27(3):24nr03828