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The decision to wean or stop abruptly should be individualized based on several factors: Reason for discontinuation : Side effects, cost, achievement of weight goals, or medical contraindications Duration of treatment : Longer treatment periods may benefit from gradual transition Weight loss achieved : Greater weight loss may require more structured discontinuation planning Presence of comorbidities : Diabetes or cardiovascular conditions may need closer monitoring Patient preference and psychological readiness : Some individuals prefer gradual adjustment While not medically necessary, a stepwise reduction over 4-8 weeks allows patients to implement behavioral strategies, adjust dietary habits, and psychologically prepare for the metabolic changes that follow discontinuation
Diabetes Care 29 , 20642071 (2006)
"This whole time I've been living life and thinking it's normal to think about food all the time and then all of a sudden, you don't think about food," Groves told "GMA" of her experience on Mounjaro
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Patients with a history of pancreatitis, endocrine tumors (MEN 2), or thyroid cancer should avoid use of semaglutide
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