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Probst L, Monnerat S, Vogt D R, Lengsfeld S, Burkard T, Meienberg A, et al

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Comparative studies between the two GLP-1/GIP dual receptor agonists showed that DA-CH5 had better effects in promoting TH+ expression and reducing IL-2 and TNF expression than DA-JC4, with no significant differences in other comparisons

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The 2024 study suggests one pathway: if statins lower active GLP-1, the bodys post-meal insulin response and satiety signaling could be blunted, tending toward higher glucose and weightespecially in those with pre-existing insulin resistance