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Diagnostic features: Deposition of pale, homogeneous, amorphous eosinophilic material

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Upon exposure of these macrophages to LPS, the enhancement of intracellular supersulfides via treatment with NAC-S2 almost completely suppressed IL-1 production, which suggests that supersulfides establish a negative feedback loop regulating NLRP3 inflammasome-mediated IL-1 production (110)

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Its short peptide structure allows researchers to work with clearly defined molecular compositions, improving experimental reproducibility and analytical accuracy

A., Servan-Schreiber, D., Panchalingam, K., & McClure, R