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In some embodiments, local otic delivery of the auris formulations or compositions described herein allows for controlled release of active agents to auris structures and overcomes the drawbacks associated with systemic administration (e.g., low bioavailability of the drug in the endolymph or perilymph, variability in concentration of the drug in the external, middle and/or internal ear)

Both GLP-1 (7-36) and GLP-1 (7-37) also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin

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Si informa che, considerata la vastit del catalogo, e il continuo aggiornamento da parte delle aziende produttrici degli articoli commercializzati, le immagini dei prodotti sono puramente indicative, potrebbero quindi non essere totalmente rappresentative del packaging differendo per dimensioni, colori o contenuto

RY: Resources, Writing original draft

International Journal of Molecular Sciences , 2021