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MatthewsJHeratLRooneyJRakoczyESchlaichMMatthewsVB: Determining the role of SGLT2 inhibition with Empagliflozin in the development of diabetic retinopathy

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For some, it causes nausea, digestive issues, or plateaus

The result can include: Hollowed cheeks or temples Deeper smile lines and under-eye hollows Skin that looks looser or slightly saggy around the jaw Fine lines that appear more pronounced This isn't unique to GLP-1 medications

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Additionally, the GH stimulatory effect on the liver to increase IGF-I secretion is accentuated by the direct GH effects in antagonizing insulin action and suppressing the anti-lipolytic actions of insulin (68)