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10.1016/j.freeradbiomed.2024.04.229 43 DegterevA.HitomiJ.GermscheidM.ChenI

WBCIL White Paper on Liposomal Glutathione, 2025

In the final step of glutathione synthesis, glycine is added to the glutamate-cysteine pair to complete the tripeptide

however, lack of interactions from the catechol group, as observed in docked poses and MD analysis, predicted to cause weak or no mh-Tyr inhibition by comparison to other selected flavonoids (EC and CH) due to rapid oxidation in the catalytic pocket of the mh-Tyr protein