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Body composition changes during weight reduction with tirzepatide in the SURMOUNT-1 study of adults with obesity or overweight

The glucagon receptor component is hypothesised to enhance energy expenditure and fat breakdown, which researchers believe may contribute to greater weight loss compared with dual or single agonists though this remains under investigation and has not been definitively established

Available retatrutide body-composition data suggest favorable fat-mass reduction and no obvious disproportionate lean-mass penalty relative to total weight loss

P., Smith, A

Your final options are to pay out of pocket for the prescription medication or explore other savings options, which well discuss below

However, it's essential to inform your healthcare provider about any thyroid conditions, as they may consider the specific effects of the medications on thyroid function