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If a vial will take more than 30 days to finish at your current dose, consider splitting the powder into multiple vials before reconstitution, or accept that the final doses may be slightly less potent

The timeline question of when side effects begin varies by individual but most people notice GI effects within the first few days of each dose increase

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Clinical data shows that starting at 2mg instead of 4mg significantly reduces GI symptom frequency and intensity

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