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10.1097/jom.0b013e3181990c2c 178 SeleciM.ScheperT.StahlF

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The clinical significance in humans is unknown, but according to the prescribing information, Wegovy is contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

The main concern is that SSRIs and SNRIs can affect appetite and weight independently, and combining them with retatrutide may amplify GI side effects in some people