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Continuing CPAP therapy is crucial for maintaining good sleep health, even as GLP-1 medications help improve overall health and reduce sleep apnea severity

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She said she hoped the expanded approval would improve insurance coverage, particularly as generic weight-loss drug alternatives can carry heart risks, but noted that if insurance comes on board with this indication, she has no idea how manufacturing will ever catch up. But, Dushay added, this might also help prioritize use of [the drugs] among those with highest-risk obesity, those who also have cardiovascular disease

"This could be another tool that we'll have in our toolbox," said Eduardo Grunvald, medical director of the UC San Diego Health Center for Advanced Weight Management

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The thermogenic effect from Retatrutides glucagon activation may partially offset this age-related metabolic decline, potentially making the medication especially valuable for women over 40