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Exploring Metabolomic Patterns in Type 2 Diabetes Mellitus and Response to Glucose-Lowering MedicationsReview

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Indeed, it has been estimated that just 10-15% of the secreted GLP-1(7-36) NH2 reaches the systemic circulation (117), with some authors reporting meager peripheral meal-induced changes in both healthy and diabetic people (118)

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Injecting into inappropriate sites can lead to poor drug absorption, increased pain, bruising, or more serious complications such as inadvertent intramuscular injection or nerve damage