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This is likely due to the more established CKD-specific evidence base available for SGLT2is [10,11,12], and the fact that FLOW evaluated semaglutide in patients receiving prior guideline-directed standard of care, limiting generalisability to GLP-1 RAs more broadly as a first-line therapy [8, 9]

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For exercise, the American Heart Association recommends three to four 40-minute sessions of moderate to vigorous intensity exercise per week for most adults

Its also important to consider lifestyle factors

Diverticulitis, an inflammatory condition affecting the colon, requires careful consideration when starting new medications that influence gastrointestinal function