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The OB GLP-1R-induced decrease in sympathetic nerve activity is GABA-dependent and relays via the PVN We next aimed to identify the mechanisms leading to the decrease in SNS activity after activation of the GLP-1R in the OB, which was confirmed by the observed increase in cFos expression in the MCL after local Ex4 injection (Fig
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Plates were then centrifuged at 800 g for 30 min, and the supernatant transferred into new plates
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