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Although the majority of desmoplastic/spindle cell melanomas demonstrate S100 protein and/or Sox10 immunoreactivity, partial/or complete loss of expression of these markers such as that observed in malignant peripheral nerve sheath tumors can be found, 20, 21 especially in metastatic cases

Dermatol Surg 31:518521 August PJ, Ferguson JE, Madan V (2011) A study of the efficacy of carbon dioxide and pigment-specific lasers in the treatment of medium-sized congenital melanocytic naevi

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