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In dark-skinned people, melanoma often appears under the fingernails or toenails, on the palms of hands or on the soles of the feet

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Circ Res 93:354363 Shi F, Wang YC, Zhao TZ, Zhang S, Du TY, Yang CB, Li YH, Sun XQ (2012) Effects of simulated microgravity on human umbilical vein endothelial cell angiogenesis and role of the PI3K-Akt-eNOS signal pathway