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There was also an improvement in the levels of low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol, and triglycerides in participants who received retatrutide compared to placebo, which did not show improvement

10.1186/1750-1326-9-40 Mol

Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR- and CAR transcription factors

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Then, prepared cell lysates were plated on a 96-well plate (Nunc) overnight at 4 C and incubated with 5% BSA PBST (NaCl 137 mM, KCl 2.7 mM, Na 2 HPO 4 10 mM, KH 2 PO 4 1.8 mM, 0.1% Tween 20) for 2 h at room temperature (RT)